Anhedonia: Preclinical, Translational, and Clinical Integration

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File Name:Anhedonia: Preclinical, Translational, and Clinical Integration
Books Type:Digital Version
Genre / Category:E-BOOKS & AUDIO BOOKS
File Size :23MB
Updated and Published:September 19, 2022

Anhedonia: Preclinical, Translational, and Clinical Integration – FREE EBOOKS DOWNLOAD

English | 2022 | ISBN: 3031096827 | 548 Pages | PDF EPUB (True) | 23.3 MB

Anhedonia is a key symptom (and often risk factor) for various neuropsychiatric disorders, including depression, schizophrenia, substance use disorders, post-traumatic stress disorders, and Parkinson’s Disease, among others. Across disorders, anhedonia has been associated with worse disease course, including poor response to pharmacological, psychological and neurostimulation treatments as well as completed suicide. Mounting evidence emerging from preclinical and translational sciences has clarified that “anhedonia” can be parsed into partially independent subcomponents, including incentive motivation, consummatory pleasure, reward learning, and effort-based decision making, pointing to distinct neurobiological substrates that could underlie anhedonic phenotypes. Taking an integrative approach that emphasizes cross-species integration and dimensional conceptualization of mental illnesses (e.g., Research Domain Criteria (RDoC)), this book represents the most comprehensive evaluation, synthesis and integration of theories and empirical findings focused on anhedonia.

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